跳到主要內容區

自由基暨粒線體醫學實驗室_老師簡介 Curriculum Vitae

 

lab home

 

             

 

 

 

更新日期 : 2022.03.14

Education

1988-1992  B.S., National Taiwan University (Taiwan)

                     College of Medicine

                     School of Medical Technology (台大醫事技術學系)

1992-1997  Ph.D., University of Kentucky (USA)

                     Graduate Center for Toxicology

                     Advisor: Dr. Daret K. St. Clair

 

Postdoctoral training
 

1997 Aug-1998 Feb  Postdoctoral scholar, University of Kentucky (USA)

                                      Graduate Center for Toxicology

                                      Mentor: Dr. Daret K. St. Clair

1998 Mar-1999 Mar  Postdoctoral Fellow, Emory University (USA)

                                      Center for Molecular Medicine

                                      Mentor: Dr. Douglas C. Wallace

 

Faculty appointment     
 
              

1999 Mar-2007 July 

Assistant professor, Department of Medical Biotechnology and Laboratory Medicine, Chang Gung University

2007 August-2016 July

 Asscoiate professor, Department of Medical Biotechnology and  Laboratory Medicine, Chang Gung University

2016 August-Present

 Professor, Department of Medical Biotechnology and  Laboratory Medicine, Chang Gung University

 

Honor, awards, and professional certificate
 
  1. Book-Coupon Award (top 5%) at National Taiwan University (1989).

  2. Certificate of the National Examination for the Professional and Skilled Person for Medical Technologist proved by Ministry of Examination, Taiwan: qualified for the exchange of licensures for being a medical technologist (1992).

  3. Young Investigator Award in the 5th Annual meeting of The Oxygen Society at Washington DC, November 22, 1998.

  4. Award of Excellent Research Paper in the 19th Joint Annual Conference of Biomedical Sciences awarded by Toxicology Society of Taiwan, April 10-11, 2004.

  5. "Excellent Teacher Award in Student Counseling"  from Chang Gung University, September, 2009.

  6. "Excellent Research Paper Award (Clinical Field)"  from Taiwan Society of Laboratory Medicine, October, 2010. 

  7. "Excellent Teacher Award in Student Counseling"  from Chang Gung University, September, 2015.

 

 

Professional affiliation and services
 
  1. Member of the Toxicology Society of Taiwan
    Member of the Society for Free Radical Research (Taiwan)

  1. Council member: 2004 January –2015 October (台灣自由基學會理事)

    Secretary-general: 2015 October –2017 July (台灣自由基學會秘書長
    Supervisor: 2018 October - 2021 October (監事)
    Standing supervisor: 2021 November - present (常務監事)

  1. Member of Taiwan Society of Mitochondrial Research and Medicine (Taiwan)
    Council member: 2006 August –2018 September (台灣粒線體醫學暨研究學會理事) 
    Standing supervisor: 2018 Octrober - 2021 October (常務監事)   

           

Invited speech
 

(1) In Taiwan

  1. The Role of Reactive Oxygen Species in Antineoplastic Agent-induced Cardiac Toxicity: A MnSOD Transgenic Mice Model. 15th Joint Annual Conference of Biomedical Sciences, March 2000, National Yong-Ming University, Taipei (invited by Taiwan Society of Toxicology).

  2. Status of oxidative stress following aneurysmal subarachnoid hemorrhage. International Conference in Oxidative Damage Marker and Antioxidant Intervention in Health and Diseases, October 29-30, 2004, Chang Gung University, Taoyuan (invited by Society for Free Radical Research, Taiwan).

  3. Mitochondrial, antioxidant enzymes, and apoptosis in the effect of anticancer drugs. Symposium on Mitochondria and Related Diseases, October 8, 2005, Holiday Inn Asia World, Taipei (invited by Taiwan Society of Neurology).

  4. Simultaneous detection of lipid-soluble antioxidants by CoulArray HPLC. Symposium on Wellness and Free Radicals. May 13, 2006, Chang Gung Memorial Hospital, Taoyuan (invited by Society for Free Radical Research, Taiwan).

  5. Effect of antimycin A on levels of coenzyme Q10 and primary antioxidant enzymes in 143B versus 143B-ρ0 Cells. First Annual Meeting of Taiwan Society of Mitochondrial Research and Medicine, August 5, 2006, Chang Gung Memorial Hospital, Kaoshung (invited by Taiwan Society of Mitochondrial Research and Medicine).

  6. Correlation of CSF F2-isoprostanes levels with poor outcome following aneurysmal subarachnoid hemorrhage in humans. January 26, 2007, Taipei (invited by Department of Teaching and Research, Taipei Veterans General Hospital/台北榮總教研部).

  7. Alterations of endogenous coenzyme Q10 levels by mitochondrial dysfunction and oxidative stress and in human astrocytomas.  Conference of Taiwan Society for Mitochondrial Research and Medicine. February 16-17, 2008, Chang Gung Memorial Hospital, Keelung (invited by Taiwan Society of Mitochondrial Research and Medicine).

  8. Regulation of endogenous coenzyme Q10 in response to oxidative stress and mitochondrial dysfunction.  January 8, 2009, Taipei (invited by Department of Pathology, Mackay Memorial Hospital/馬偕紀念 醫院病理科).

  9. Mitochondrial DNA and Medical Research. March 23, 2009, Taipei (Invited by Investigation Bureau, Ministry of Justice/法務部調查局).
     

  10. F2-isoprostanes and F4-neurprostanes: a specific markers of oxidative damage and the clinical application. May 26, 2009, Taoyuan (Invited by Saint Paul's Hospital/財團法人天主教聖保祿修女會醫院).

  11. Features of human mitochondrial DNA and its mutation detections. Workshop in DNA Identification. September 25, 2009, Central Police University/ 中央警察大學, Taoyuan (Invited by Taiwan Academy of Forensic Sciences/ 中華民國鑑識學會).

  12. F2-isoprostanes and F4-neuroprostanes in clinical studies.  台大醫技系55週年系慶暨先導型轉譯醫學研討會. February 26, 2011, National Taiwan University, Taipei, Taiwan (invited by Department of Clinical Laboratory Sciences and Medical Biotechnology, National Taiwan University).

  13. Elevated levels of F2-isoprostanes and F4-neuroprostanes in plasma and cerebrospinal fluid of patients with traumatic brain injury.  Meeting of the Society of Free Radical Research-Taiwan, October 20, 2012, Taipei, Taiwan.

  14. Up-regulation of coenzyme Q10 levels and expression of COQ genes in the cybrid with pathogenic mtDNA T8993G mutation. 7th International Symposium on Genomic Medicine of Changhua Christian Hospital and Annual Meeting of Taiwan Society for Mitochondrial Research and Medicine, October 26-27, 2012, Changhua and Taichung, Taiwan.

  15. Regulation of coenzyme Q10 levels and expression of PDSS and COQ genes in human cells in response to mitochondrial and oxidatve stresses. Biennial Meeting of Society for Free Radical Research Asia. Oct 16-19, 2013, Taoyuan, Taiwan.

  16. Roles of the human COQ5 protein in the alterations of coenzyme Q10 levels under conditions of mitochondrial dysfunction and oxidative stress. 10th International Symposium of Genomic Medicine of Changhua Christian Hospital and Meeting of Taiwan Society for Mitochondrial Research and Medicine, September 24-25, 2016, Changhua, Taiwan.

  17. F2-isoprostanes and F4-neuroprostanes: Golden markers for clinical research. 10th International Symposium of Genomic Medicine of Changhua Christian Hospital and Annual Meeting of Taiwan Society for Mitochondrial Research and Medicine, June 29-30, 2018, Changhua, Taiwan. 

  18. Characterization on various PDSS and COQ proteins for biosynthesis of coenzyme Q10 in human cells. Annual Meeting ofTaiwan Society for Mitochondrial Research and Medicine, November 9, 2019, National Taiwan University College of Medicine, Taipei, Taiwan.

 

(2)  Outside Taiwan
​​​​​​

  1.       The Studies of Oxidative Stress or Antioxidant Enzymes for Two Human Diseases in Neurosurgery : Aneurysmal Subarachnoid Hemorrhage and Astrocytoma. November 24, 2008, Graduate Center for Toxicology, University of Kentucky, Lexington, KY, USA (invited by University of Kentucky).

  2.       Correlation of F2-isoprostanes and F4-neuroprostanes levels in cerebrospinal fluid with clinical severity of patients following aneurysmal subarachnoid hemorrhage.  Society for Free Radical Research (SFRR) International's Free Radical School in Japan 2009, September 2-6, 2009, Niigata, Japan (invited by Society for Free Radical Search Japan).

  3.        Effect of mitochondrial dysfunction and oxidative stress on endogenous levels of coenzyme Q10 in human cells. The 7th Conference of the Asian Society for Mitochondrial Research and Medicine (ASMRM)/International Conference on Mitochondria, Life and Intervention 2010. December 15-18, 2010, Fukuoka Internal Congress Center, Fukuoka, Japan (invited by ASMRM/Japanese Society of Mitochondrial Research and Medicine).

  4.        F2-isoprostanes and F4-neuroprostanes in non-traumatic subarachnoid hemorrhage in humans and rats.  Joint Meetings of the 5th Biennial Meeting of the Society for Free Radical Research –Asia (SFRR-Asia) and the 8th Conference of the ASMRM, August 31-Sepetember 4, 2011, Kagoshima, Japan (invited by SFFR-Asia and ASMRM).

 

 

 

  lab home

 

 

瀏覽數: