自由基暨粒線體醫學實驗室_實驗成員 Laboratory Members
更新日期 : 2024.07.19
Research Assitants (專任研究助理)
| 碩士級專任研究助理 | 吳 昕 燏 |
| 碩士級專任研究助理 | 吳 俊 諺 |
Graduate Students (碩士生)
|
醫 技 所 碩一 |
姜 淳 軒 |
|
醫 技 所 碩一 |
陳 彥 蓁 |
Undergraduate Students (大學專題生)
| 醫 技 系 四 年 級 | 余 紫 琦 |
| 醫 技 系 四 年 級 | 盧 韋 伶 |
| 醫 技 系 二 年 級 | 賴 佩 岑 |
| 醫 技 系 二 年 級 | 李 冠 霆 |
Former Master Students (前碩士生)
|
畢業日期
(Graduation date) |
姓名
(Name) |
系所
|
論文題目
(Titles of Thesis) |
| 2003.07 | 李佳珮 (現改名 李欣樺） |
基醫所 生化及分生組 |
The role of primary antioxidant enzymes in the nechanism of acquired resistance to bleomycin in human oral squamous cell carcinoma |
| 2004.07 | 許意慈 | 生技所 |
Status of oxidative stress following aneurysmal subarachnoid hemorrhage
|
| 2005.07 | 陳炳憲 | 生技所 | Levels of antioxidant enzymes and lipid-soluble antioxidants in different grades of human astrocytomas |
| 2006.01 | 陳秋萍 | 生技所 | Suppression of apoptosis and cell cycle arrest induced by bleomycin in bleomycin-resistant human oral squamous cell carcinoma |
| 2006.07 | 陳世偉 | 生技所 | Effect of antimycin A on levels of reactive oxygen species, coenzyme Q10 and primary antioxidant enzymes in 143B versus 143B-ρ0 cells |
| 2007.01 | 王儷瑾 | 生技所 | Compensatory alteration of biogenesis genes in response to mtDNA depletion |
| 2008.07 | 謝育萍 | 生技所 | Analysis of F4-neuroprostanes, F2-isoprostanes, or lipid-soluble antioxidants in humans and rats following non-traumatic subarachnoid hemorrhage |
| 2008.07 | 劉佳琪 | 生技所 | Coenzyme Q10 and bleomycin resistance in human oral cancer cells |
|
2009.07
|
陳志威
|
生技所
|
Alteration of endogenous coenzyme Q10 and COQ genes in the cybrid with pathogenic mtDNA T8993G mutation and oxidative strees
|
| 2010.07 | 徐瑋謙 | 生技所 | Confirmation of novel somatic mitochondrial DNA mutations in human astrocytoma tissues by denaturing HPLC and pyrosequencing |
| 2010.07 | 陳頲瑋 | 生技所 | Level of F2-isoprostanes and F4-neuroprostanes in cerebrospinal fluid of patients with traumatic brain injury |
| 2012.07 |
李雪莉 |
生技所 | Potential effect of nuclear mtDNA sequence on detecting mtDNA mutations by traditional DHPLC Surveyor Nuclease with DHPLC detection |
| 2013.07 | 甘佳琪 | 生技所 | Effect of the chemical uncoupler FCCP on endogenous levels of coenzyme Q10 in normal human WI38 versus transformed WI38 (VA13) cells |
| 2017.07 | 李思嫻 | 生技所 | Comparison on the roles of COQ3 and COQ7 proteins in maintaining coenzyme Q10 levels, the stability of other COQ proteins, and mitochondrial functions in human cells |
| 2017.07 | 馮郁琇 | 生技所 |
The study on the changes of endogenous coenzyme Q10 levels in coenzyme Q10-deficient human cells after the addition of exogenous coenzyme Q9 |
| 2020.07 | 葉雯瑜 | 生技所 |
Characterization of PDSS and COQ proteins for the search of coenzyme Q synthome in human cells |
| 2022.07 | 張峻為 | 生技所 | Effect of immunosuppressive therapy on paraquat-induced oxidative stress and inflammatory responses in mouse tissues |
Former Undergraduate Students
(前大學專題生)
|
指導期間
(Periods) |
姓名
(Name)
|
論文題目
(Titles of Undergraduate Thesis)
|
|
1999.08~
2000.12 |
許意慈
|
Establishment of the method for detecting urinary F2-isoprostanes to study lipid peroxidation and human diseases
|
|
1999.08~
2000.12 |
陳鋺菁
|
Levels of lipid peroxidation and mtDNA damage in normal versus transformed cells following bleomycin treatment
|
|
1999.02~
2001.12 |
許惠茹
|
Expression of mtDNA genes and activity of antioxidant enzyme MnSOD in cisplatin-resistant oral cancer cells
|
|
1999.02~
2001.12 |
莊喬絨
|
Activities of primary antioxidant enzymes in bleomycin-resistant oral cancer cells
|
|
2001.08~
2001.12 |
陳彥名
|
Effect of mtDNA depletion on activities of primary antioxidant enzymes in human osteosarcoma cells
|
|
2000.09~
2002.12 |
陳佩如
|
Effect of cisplatin on the expression of mitochondrial genes and activities of antioxidant enzymes in normal versus transformed human cells
|
|
2000.09~
2002.12 |
張曉旻
|
Effect of bleomycin on the expression of mitochondrial genes and activities of Mn superoxide dismutase in normal vs. transformed human cells
|
|
2001.09~
2003.12 |
陳世偉
|
Effect of antimycin A on levels of F2-isoprostanes and mitochondrial superoxide dismutase in 143B-TK- vs. 143B-ρ0 cells
|
|
2001.10~
2003.12 |
湯宜家
|
The role of mtDNA depletion in cisplatin-induced cytotoxicity in human osteosarcoma cells
|
|
2002.09~
2004.12 |
陳柏彰
|
Suppression of apoptosis and the cross resistance between bleomycin and cisplatin in oral cancer cell
|
|
2003.09~
2005.12 |
謝育萍
|
Apoptosis pathways induced by cisplatin in 143B versus 143B-ρ0 cells
|
|
2003.09~
2005.12 |
涂雅琪
|
Levels of coenzyme Q10 in bleomycin-resistant oral cancer cells
|
|
2003.09~
2005.12 |
柯武賢
|
Effect of bleomycin on glutathione peroxidase in a human oral cancer cell line and its bleomycin-resistant clones
|
|
2004.09~
2006.12 |
陳志威
|
Expression of peroxiredoxin/thioredoxin reductase system in human oral cancer cells with acquired bleomycin resistance
|
|
2004.09~
2006.12 |
李習慈
|
Effect of antimycin A on protein levels of primary antioxidant enzymes in 143B versus 143-ρ0 cells
|
|
2004.09~
2006.12 |
徐瑋謙
|
The detection of mitochondrial DNA mutations in human astrocytomas
|
|
2005.09~
2008.12 |
李巧玲
|
Effect of mtDNA deficiency on levels of reactive oxygen species , antioxidant enzymes and treatment of antimycin A
|
|
2005.09~
2008.12 |
陳鋒源
|
Effect of hydrogen peroxide on endogenous levels of coenzyme Q10 and COQ genes
|
|
2005.09~
2008.12 |
陳柏源
|
Effect of inhibition of mitochondrial complex I on levels of primary antioxidant enzymes
|
|
2006.09~
2008.12 |
張竣偉
|
Comparison of mtDNA sequences in human astroctyomas before and after radiotherapy
|
|
2006.09~
2008.12 |
陳韻如
|
Effect a mitochondrial uncoupler on levels of coenzyme Q10 and its biosynthetic genes in 143B cells
|
|
2008.06~
2010.05 |
廖筱嫚
|
Effect a rotenone on levels of endogenous CoQ10 and COQ genes in human cells
|
|
2007.09~
2009.12 |
王子元
|
Effect of antimycin A on mRNA level of PDSS and COQ genes in 143B versus 143B--ρ0 cells
|
|
2009.09~
2011.12 |
薛郁馨 | Confirmation of somatic missense mtDNA mutations in human astrocytoma by pyrosequencing |
|
2009.09~
2011.12 |
陳俊堂 | Influence of augmented oxidative stress on the suppressive effect of antimycin A on coenyzme Q10 levels |
|
2009.09~
2011.12 |
黃悅筑 | Purification of human COQ4 protein for production of polyclonal antibody |
|
2010.09~
2012.12 |
陳崇聖 | Effect of oligomycin on levels of endogenous coenzyme Q10 in 143B cells |
| 2013.02~ 2014.12 |
黃駿涵 | Effect of the knockdown of the COQ8 gene on coenyzme Q10 levels and expression of other PDSS and COQ genes in human cells |
| 2013.02~ 2014.12 |
馮郁琇 | Effect of COQ9 knockdown on coenyzme Q10 levels and oxidative stree induced by organic peroxid in human cells |
| 2013.09~ 2015.12 |
呂亮萱 |
Effect of coenzyme Q10 supplementation on the expression of COQ5 and PPARGC1A in cybrids with the A8344G mutation of mitochondrial DNA
|
| 2013.09~ 2015.12 |
黃國誠 | Effect of PPARGC1A knockdown on CoQ10 levels and expression of PDSS and COQ genes in human 143B cells without or with FCCP treatment |
| 2013.09~ 2015.12 |
陳逸萱 |
Alterations in the levels of coenzyme Q10 and the effect of COQ5 knockdown in cybrids with pathogenic A3243G mutation of mitochondrial DNA
|
| 2014.09~ 2016.12 |
景琦 | The role of the COQ3 protein in maintaining coenzyme Q10 levels and its relationship with other COQ proteins in human cells |
| 2014.09~ 2016.12 |
吳以新 | Levels of coenzyme Q10 and the expression of its terminal biosynthetic genes after the induction of lipid peroxidation in human cells by an organic peroxide |
|
2015.09~ 2017.12 |
葉雯瑜 | Alterations in the coenzyme Q10 levels and COQ proteins levels after transient knockdown of PDSS1 and PDSS2 in human 143B cells |
|
2015.09~ 2017.12 |
張興洺 | levels of the oxidized and reduced forms of coenzyme Q10 and levels of PDSS and COQ proteins in human 143B cells after antimycin A treatment |
|
2016.09~ 2018.12 |
許家慈 | Alterations in the levels of coenzyme Q10 levels, PDSS proteins, and COQ protein in cybrids containing the mitochondrial DNA A3243G mutation |
|
2017.09~ 2019.12 |
張峻為 | Comparison on the lipid peroxidation levels in tissues of paraquat-poisoned mice with and without immunosuppression therapy |
|
2017.09~ 2019.12 |
郭沛昀 | Effects of exogenous coenzyme Q on lipid peroxidation and alterations of endogenous coenyme Q10 levels induced by an organic peroxide in human cells |
|
2018.09~ 2020.12 |
陳宥蓉 | Regulation of endogenous coenzyme Q10 and its biosynthetic proteins yrdimidine requirement under the condition of mitochondrial complex III inhbition. |
|
2019.09~ 2021.12 |
吳孟涵 | Status of protein complexes containing PDSS2 or Several COQ proteins in cybrids with pathogenic mitochondrial DNA mutations |
|
2019.09~ 2021.12 |
簡妤安 | Effect of mitochondrial complex I inhibition on levels of coenzyme Q 10 and its biosynthetic proteins in human cells |
|
2020.09~ 2022.12 |
吳昱諄 | Effect of the accumulated intermediates of coenzyme Q 10 biosynthesis caused by human COQ7 deficiency on the electron transport chain |
|
2021.09~ 2023.12 |
姜淳軒 |
Evaluation of lipid peroxidaiton status in mouse body fluids, kidneys, and brains following chronic lead poisoning without and with DMPS chelation therapy |
|
2021.09~ 2023.12 |
陳彥蓁 |
Identification of Coq6-containing protein complex in the mitochondria from mouse cells |
Former Outstanding Research Assistants
(前特優專任研究助理)
|
工作期間
(Periods) |
姓名
(Name)
|
|
2001.08 ~ 2002.07
|
許意慈
|
| 2002.08 ~ 2004.04 | 張慧敏 |
| 2006.08 ~ 2010.04 |
薛安利
|
| 2006.09 ~ 2011.07 | 黃渝翔 |
| 2010.08 ~ 2011.10 | 徐瑋謙 |
| 2010.08 ~ 2012.06 | 陳頲瑋 |
| 2013.08 ~ 2016.02 | 甘佳琪 |
| 2011.08 ~ 2016.07 | 劉儀君 |
| 2007.09 ~ 2017.06 | 衛星如 |
| 2018.09 ~ 2019.09 | 楊偲羚 |
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