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自由基暨粒線體醫學實驗室_實驗成員 Laboratory Members

 

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更新日期 : 2022.03.14

Research Assitants (專任研究助理)
碩士級專任研究助理 吳 昕 燏
碩士級專任研究助理 吳 俊 諺
   

 

Graduate Students (研究生)
 
 醫 技 系       碩 二    張 峻 為
 
 
 
 
 
Undergraduate Students (大學專題生)
 
醫         年 級 吳 孟 涵
 技        四 年 級 簡 妤 安
 技         三 年 級 吳 昱 
 技 系        二 年 級 姜 淳 軒
 技 系        二 年 級

陳 彥

  •  
 
Former Master Students (前碩士生)
 
 
畢業日期
(Graduation date)
姓名
(Name)
系所
論文題目
(Titles of Thesis)
2003.07 李佳珮
(現改名
李欣樺)
基醫所
生化及分生組
The role of primary antioxidant enzymes in the nechanism of acquired resistance to bleomycin in human oral squamous cell carcinoma
2004.07 許意慈 生技所
Status of oxidative stress following aneurysmal subarachnoid hemorrhage
2005. 07 陳炳憲 生技所 Levels of antioxidant enzymes and lipid-soluble antioxidants in different grades of human astrocytomas
2006. 01 陳秋萍 生技所 Suppression of apoptosis and cell cycle arrest induced by bleomycin in bleomycin-resistant human oral squamous cell carcinoma
2006. 07 陳世偉 生技所 Effect of antimycin A on levels of reactive oxygen species, coenzyme Q10 and primary antioxidant enzymes in 143B versus 143B-ρ0 cells
2007. 01 王儷瑾 生技所 Compensatory alteration of biogenesis genes in response to mtDNA depletion
2008. 07 謝育萍 生技所 Analysis of F4-neuroprostanes, F2-isoprostanes, or lipid-soluble antioxidants in humans and rats following non-traumatic subarachnoid hemorrhage
2008. 07 劉佳琪 生技所 Coenzyme Q10 and bleomycin resistance in human oral cancer cells
2009. 07
陳志威
生技所
Alteration of endogenous coenzyme Q10 and COQ genes in the cybrid with pathogenic mtDNA T8993G mutation and oxidative strees
2010. 07 瑋謙 生技所 Confirmation of novel somatic mitochondrial DNA mutations in human astrocytoma tissues by denaturing HPLC and pyrosequencing
2010. 07 陳頲瑋 生技所 Level of F2-isoprostanes and F4-neuroprostanes in cerebrospinal fluid of patients with traumatic brain injury
2012. 07

李雪莉

生技所 Potential effect of nuclear mtDNA sequence on detecting mtDNA mutations by traditional DHPLC Surveyor Nuclease with DHPLC detection
2013. 07 甘佳琪 生技所 Effect of the chemical uncoupler FCCP on endogenous levels of coenzyme Q10 in normal human WI38 versus transformed WI38 (VA13) cells
2017. 07 李思嫻 生技所 Comparison on the roles of COQ3 and COQ7 proteins in maintaining coenzyme Q10 levels, the stability of other COQ proteins, and mitochondrial functions in human cells
2017. 07 馮郁琇 生技所

The study on the changes of endogenous coenzyme Q10 levels in coenzyme Q10-deficient human cells after the addition of exogenous coenzyme Q9

2020. 07 葉雯瑜 生技所

Characterization of PDSS and COQ proteins for the search of coenzyme Q synthome in human cells

 
 
Former Undergraduate Students
(前大學專題生)
 
指導期間
(Periods)
姓名
(Name)
論文題目
(Titles of Undergraduate Thesis)
1999.08~
2000.12
許意慈
Establishment of the method for detecting urinary F2-isoprostanes to study lipid peroxidation and human diseases
1999.08~
2000.12
陳鋺菁
Levels of lipid peroxidation and mtDNA damage in normal versus transformed cells following bleomycin treatment
1999.02~
2001.12
許惠茹
Expression of mtDNA genes and activity of antioxidant enzyme MnSOD in cisplatin-resistant oral cancer cells
1999.02~
2001.12
莊喬絨
Activities of primary antioxidant enzymes in bleomycin-resistant oral cancer cells
2001.08~
2001.12
陳彥名
Effect of mtDNA depletion on activities of primary antioxidant enzymes in human osteosarcoma cells
2000.09~
2002.12
陳佩如
Effect of cisplatin on the expression of mitochondrial genes and activities of antioxidant enzymes in normal versus transformed human cells
2000.09~
2002.12
張曉旻
Effect of bleomycin on the expression of mitochondrial genes and activities of Mn superoxide dismutase in normal vs. transformed human cells
2001.09~
2003.12
陳世偉
Effect of antimycin A on levels of F2-isoprostanes and mitochondrial superoxide dismutase in 143B-TK- vs. 143B-ρ0 cells
2001.10~
2003.12
湯宜家
The role of mtDNA depletion in cisplatin-induced cytotoxicity in human osteosarcoma cells
2002.09~
2004.12
陳柏彰
Suppression of apoptosis and the cross resistance between bleomycin and cisplatin in oral cancer cell
2003.09~
2005.12
謝育萍
Apoptosis pathways induced by cisplatin in 143B versus 143B-ρ0 cells
2003.09~
2005.12
涂雅琪
Levels of coenzyme Q10 in bleomycin-resistant oral cancer cells
2003.09~
2005.12
柯武賢
Effect of bleomycin on glutathione peroxidase in a human oral cancer cell line and its bleomycin-resistant clones
2004.09~
2006.12
陳志威
Expression of peroxiredoxin/thioredoxin reductase system in human oral cancer cells with acquired bleomycin resistance
2004.09~
2006.12
李習慈
Effect of antimycin A on protein levels of primary antioxidant enzymes in 143B versus 143-ρ0 cells
2004.09~
2006.12
徐瑋謙
The detection of mitochondrial DNA mutations in human astrocytomas
2005.09~
2008.12
李巧玲
Effect of mtDNA deficiency on levels of reactive oxygen species , antioxidant enzymes and treatment of antimycin A
2005.09~
2008.12
陳鋒源
Effect of hydrogen peroxide on endogenous levels of coenzyme Q10 and COQ genes
2005.09~
2008.12
陳柏源
Effect of inhibition of mitochondrial complex I on levels of primary antioxidant enzymes
2006.09~
2008.12
張竣偉
Comparison of mtDNA sequences in human astroctyomas before and after radiotherapy
2006.09~
2008.12
陳韻如
Effect a mitochondrial uncoupler on levels of coenzyme Q10 and its biosynthetic genes in 143B cells
2008.06~
2010.05
廖筱嫚
Effect a rotenone on levels of endogenous CoQ10 and COQ genes in human cells
2007.09~
2009.12
王子元
Effect of antimycin A on mRNA level of PDSS and COQ genes in 143B versus 143B--ρ0 cells
2009.09~
2011.12
薛郁馨 Confirmation of somatic missense mtDNA mutations in human astrocytoma by pyrosequencing
2009.09~
2011.12
陳俊堂 Influence of augmented oxidative stress on the suppressive effect of antimycin A on coenyzme Q10 levels
2009.09~
2011.12
黃悅筑 Purification of human COQ4 protein for production of polyclonal antibody
2010.09~
2012.12
陳崇聖 Effect of oligomycin on levels of endogenous coenzyme Q10 in 143B cells
2013.02~
2014.12
黃駿涵 Effect of the knockdown of the COQ8 gene on coenyzme Q10 levels and expression of other PDSS and COQ genes in human cells
2013.02~
2014.12
馮郁琇 Effect of COQ9 knockdown ocoenyzme Q10 levels and oxidative stree induced by organic peroxid in human cells
2013.09~
2015.12

呂亮萱

Effect of coenzyme Q10  supplementation on the expression of COQ5 and PPARGC1A in cybrids with the A8344G mutation of mitochondrial DNA
2013.09~
2015.12
黃國誠 Effect of PPARGC1A knockdown on CoQ10  levels and expression of PDSS and COQ genes in human 143B cells without or with FCCP treatment
2013.09~
2015.12
陳逸萱
Alterations in the levels of coenzyme Q10  and the effect of COQ5 knockdown in cybrids with pathogenic A3243G mutation of mitochondrial DNA
2014 .09~
2016.12
景琦 The role of the COQ3 protein in maintaining coenzyme Q10 levels and its relationship with other COQ proteins in human cells
2014 .09~
2016.12
吳以新 Levels of coenzyme Q10 and the expression of its terminal biosynthetic genes after the induction of lipid peroxidation in human cells by an organic peroxide

2015 .09~

2017 .12

葉雯瑜 Alterations in the coenzyme Q10 levels and COQ proteins levels after transient knockdown of PDSS1 and PDSS2 in human 143B cells

2015 .09~

2017 .12

張興洺 levels of the oxidized and reduced forms of coenzyme Q10 and levels of PDSS and COQ proteins in human 143B cells after antimycin A treatment

2016 .09~

2018 .12

許家慈 Alterations in the levels of coenzyme Q10 levels, PDSS proteins, and COQ protein in cybrids containing the mitochondrial DNA A3243G mutation

2017 .09~

2019 .12

張峻為 Comparison on the lipid peroxidation levels in tissues of paraquat-poisoned mice with and without immunosuppression therapy

2017 .09~

2019 .12

郭沛 Effects of exogenous coenzyme Q on lipid peroxidation and alterations of endogenous coenyme Q10 levels induced by an organic peroxide in human cells

2018 .09~

2020 .12

陳宥蓉 Regulation of endogenous coenzyme Q10 and its biosynthetic proteins yrdimidine requirement under the condition of mitochondrial complex III inhbition.
 
 
 
 
Former Outstanding Research Assistants
(前特優專任研究助理)

 

工作期間
 (Periods)
姓名
(Name)
2001.08 ~ 2002.07
許意慈
2002.08 ~ 2004.04 張慧敏
2006.08 ~ 2010.04
薛安利
2006.09 ~ 2011.07 黃渝翔
2010.08 ~ 2011.10 徐瑋謙
2010.08 ~ 2012.06 陳頲瑋
2013.08 ~ 2016.02 甘佳琪
2011.08 ~ 2016.07 劉儀君
2007.09 ~ 2017.06 衛星如
2018.09 ~ 2019.09 楊偲羚
 
 

 

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