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Chung-Ming chang


Chung-Ming Chang

chung-ming chang

Highest Degree

Ph. D., Degree in Animal Genetics, Institut National Agronomique Paris-Grignon, France

Areas of Specialty

Emerging and re-emerging viral infections, genomics, molecular genetics, zoonotic diseases

Office Phone


Lab phone


Research website:

Emerging Viral Infection & Genetic Biodiversity Laboratory




Lab & Research Interest

Assistant professor Chung-Ming Chang is a veterinarian; he received his bachelors and masters degrees in Veterinary Medicine from National Taiwan University. He has another masters degree in Veterinary Clinical Medicine with a specialty in avian pathology from Ecole Nationale Vétérinaire d’Alfort, France. He earned his Ph.D. in Animal Genetics from Institut National Agronomique Paris-Grignon, France. He identified one endogenous retroviral insertion in chicken which is complete associated with the recessive white mutation. Before joining the Research Center for Emerging Viral Infections (RCEVI) at Chang Gung University, he was a researcher at Pasteur Institute, Paris, and the French National Center for Scientific Research (CNRS), where he was in charge of a research program on influenza viruses in wild birds.

One of the research interests of Chung-Ming Chang is influenza, both in human and animals, with an emphasis on ecological and epidemiological studies; another interest is the study of human endogenous retroviruses which could be associated with certain autoimmune and cancer diseases. Professor Chang has been instrumental in establishing collaborative research programs between Chang-Gung University and French partners. More recently, he became the project leader of a Taiwan-Czech bilateral research project related to human cancers; high throughput sequencing technology and bioinformatics approaches are being used in the project. Outside the laboratory and classroom, Professor Chang enjoys spending time with his family, traveling and tasting French cuisine.



  1. Vidic, J., Manzano, M., Chang, C.M. and JaffrezicRenault, N. (2017). Advanced biosensors for detection of pathogens related to livestock and poultry. Veterinary Research. 48:11. (SCI)
  2. Zhang, H., Chang, C.M., Shen K.N., Xian, W., Hsiao, C.D (2016). Identification of myogenic regulatory genes in the muscle transcriptome of beltfish (Trichiurus lepturus): A major commercial marine fish species with robust swimming ability. Genomics Data. 8, 81-84 (co-first author)
  3. Luo J.D., Chang Y.J., Chang C.M., You, J.F., Wei, P.L., Chiou, C.C (2016). GeneGazer: A Toolkit integrating two pipelines for personalized profiling and biosignature identification. Cancer Genomics Proteomics. 03-04;13(2):141-150 (SCI)
  4. Tseng, C.H., Tsai, H.J., and Chang, C.M* (2014). A Complete Molecular Diagnostic Procedure for Applications in Surveillance and Subtyping of Avian Influenza Virus.Biomed Research International. 2014, 653056. (SCI) (*correspondence)
  5. Pačes J., Huang Y-T., Pačes V., Ridl J and Chang, C-M* (2013) New Insight into Transcription of Human Endogenous Retroviral Elements. New Biotechnology, 30(3): 314-318.(SCI) (*correspondence)
  6. Su, L-C., Chang, C-M., Tseng, Y-L., Chang, Y-F., Li, Y-C., Chang, Y-S., Chou, C (2012)  Rapid and Highly Sensitive Method for Influenza A (H1N1) Virus Detection. Analytical Chemistry. 84, 3914-3920. (SCI) (Co-First Author)
  7. Chang C-S., Chen C-F., Berthouly-Salazar C., Chazara  O., Lee Y-P., Chang C-M., Chang K-H., Bed_Hom B., and Tixier-Boichard M (2011) A global analysis of molecular markers and phenotypic traits in local chicken breeds in Taiwan. Animal Genetics, 43, 172–182 (SCI)
  8. Chen Y-T, Tsao Z, Chang S-T, Juang R-H, Wang L-C, Chang C-M, Wang C-H. (2012) Development of an antigen-capture enzyme-linked immunosorbent assay using monoclonal antibodies for detecting H6 avian influenza viruses. Journal of Microbiology, Immunology and Infection. 45, 243-247 (SCI)
  9. Tsai T-S., Huang M-Y, Chang Y-T, Wang C-Y, Lin J-L, Hung P-C, Lin S-P, Sun C-F, Wang W-S, Chang C-M, Chang S-C, and Chu D-C (2011). High-resolution melting analysis is a more effective approach for screening TSC genes mutations. Genetic Testing and Molecular Biomarkers 15, 415-421. (SCI)
  10. Wu Y P., Chang C-M., Hung C Y., Tsai M C, Schuyler S C., and Wang R Y. (2011). Japanese encephalitis virus co-opts the ER-stress response protein GRP78 for viral infectivity. Virology Journal  8, 128. (SCI)(Co-First authur)
  11. Chang S-C, Chang C-M, Huang Y-C, Chiu C-H, Shih S-R, and Lin T-Y (2010). Preexisting antibodies against pandemic H1N1 2009 virus in Taiwan. Clinical Infectious Diseases 51,1465-7. (SCI)
  1. Chiou C-C., Chen T-L., Tsao K-C., Shih S-R., Huang C-G., Huang Y-L & Chang C-M*. (2010) Detection of pandemic (H1N1) 2009 influenza virus by allele discrimination. Clinica Chimica Acta 411:1080-3.(SCI) (*correspondence)
  2. Huang K.S., Lee S.E., Yeh Y., Shen G.S., Mei E. & Chang C-M*. (2010) Taqman real-time quantitative PCR for identification of western flower thrip (Frankliniella occidentalis) for plant quarantine. Biology Letters,  6:555-7 (SCI)(*correspondence)
  3. Lebarbenchon C., Chang C-M., Grandhomme V., Dietrich M., Kayser Y., Elguero E., Renaud F., Thomas F. & van der Werf S., Michel Gauthier-Clerc M. (2010) Avian Influenza Circulation in the Camargue (South of France) During the 2006–07 Season. Avian Diseases 54:446–9, (SCI)
  4. Roche B., Lebarbenchon C., Gauthier-Clerc M., Chang C-M., Thomas F., Renaud F., van der Werf S. & Guégan J.F. (2009) Water-borne transmission drives avian influenza dynamics in wild birds: the case of the 2005-2006 epidemics in the Camargue area. Infection Genetics and Evolution 9, 800-5. (SCI)
  5. Chang C-M*., Lebarbenchon C., Gauthier-Clerc M., Le Bohec C., Beaune D., Le Maho Y. & van der Werf S. (2009) Molecular surveillance for avian influenza A virus in king penguins (Aptenodytes patagonicus). Polar Biology 32, 663-5. (SCI) (*correspondence)
  6. Lebarbenchon C., Chang C-M* (Co-correspondence)., Gauthier-Clerc M., Thomas F., Renaud F. & van der Werf S. (2009) H9N2 avian influenza virus in a Mediterranean gull. Journal of Molecular and Genetic Medicine 3, 121-3.
  7. Lebarbenchon C., van der Werf S., Thomas F., Aubin J.T., Azebi S., Cuvelier F., Jeannin P., Roca V., Chang C-M., Kayser Y., Roche B., Guegan J.F., Renaud F. & Gauthier-Clerc M. (2007) Absence of detection of highly pathogenic H5N1 in migratory waterfowl in southern France in 2005-2006. Infection, genetics and evolution 7, 604-8. (SCI)
  8. Lebarbenchon C., Chang C-M., van der Werf S., Aubin J.T., Kayser Y., Ballesteros M., Renaud F., Thomas F. & Gauthier-Clerc M. (2007) Influenza A virus in birds during spring migration in the Camargue, France. Journal of Wildlife Diseases 43, 789-93. (SCI)
  9. Chang C-M*., Furet J.P., Coville J.L., Coquerelle G., Gourichon D. & Tixier-Boichard M. (2007) Quantitative effects of an intronic retroviral insertion on the transcription of the tyrosinase gene in recessive white chickens. Animal Genetics 38, 162-7. (SCI) (*correspondence)
  10. Chang C-M*., Coville J.L., Coquerelle G., Gourichon D., Oulmouden A. & Tixier-Boichard M. (2006) Complete association between a retroviral insertion in the tyrosinase gene and the recessive white mutation in chickens. BMC Genomics 7, 19. (SCI) (*correspondence)
  11. Wang C-H. & Chang C-M. (2000) Pathogenicity and gene analysis of adenovirus from pigeons with inclusion body hepatitis.  Journal of Veterinary Medical Science 62, 989-93. (SCI)
  12. Wang C.H. & Chang C-M. (2000) Two nucleic acid detecting methods applied in pigeon adenovirus. Journal of the Chinese Society of Veterinary Science 26, 204-12.